Cardiology and Angiology: An International Journal <p style="text-align: justify;"><strong>Cardiology and Angiology: An International Journal (ISSN:&nbsp;2347-520X)</strong>&nbsp;aims to publish high quality papers (<a href="/index.php/CA/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of ‘Cardiology and Angiology research’. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> en-US (Cardiology and Angiology: An International Journal) (Cardiology and Angiology: An International Journal) Sat, 17 Jul 2021 12:22:41 +0000 OJS 60 Large Psoas Hematoma Complicating Anti-coagulant Therapy Poses a Diagnostic and Therapeutic Challenge <p>Spontaneous psoas haematoma in patients on anti-coagulant therapy is a rare phenomenon. It poses a real diagnostic problem and a real therapeutic challenge. We report the case of a 51 year old patient, under anti-vitamin K (acenocoumarone) following a stenosante and tricuspid mitral plasty who presented with right lumbar pain radiating to the lower limb leading to functional impotence. Clinically, he was hemodynamically stable with a hematoma measuring 88x29 mm and extending to 161 mm. The ultrasound scan showed a large collection at the expense of the lumbar psoas muscle and the CT scan showed a swollen appearance of the right psoas muscle in its iliac portion. Management was conservative: discontinuation of anti-vitamin K, bed rest, antibiotic therapy, and monitoring (clinical, biological and radiological). The ultimate outcome was favourable.</p> Brahim Nassour A., Hissein Hagguir, Noel Mahoungou, Harouna Seydou, Fadoul Adam, Salim Arous, Leila Azzouzi, Abdel Nasser Dirghil, Rachida Habbal ##submission.copyrightStatement## Wed, 17 Nov 2021 00:00:00 +0000 A Novel Method for Measuring Myocardial Performance Index using Non-contact Ballistocardiogram System <p><strong>Aim: </strong>The aim was to validate the Systolic Time Intervals (STI) measured by Ballistocardiography (BCG) with STI derived from simultaneously performed Transthoracic Echocardiogram (TTE) and attempt to create an AI algorithm that automatically calculates Tei Index from BCG tracings.</p> <p><strong>Study design:</strong>&nbsp; Cross-sectional study.</p> <p><strong>Place and Duration of Study: </strong>Department of Cardiology and Department of Electrophysiology of Sri Jayadeva Institute of Cardiovascular Sciences &amp; Research, Bangalore, India, between January 2020 and January 2021.</p> <p><strong>Methodology:</strong> Two hundred seventy-four patients with clinically indicated TTE were enrolled in the study, average age was 52. Simultaneous recordings on BCG and TTE were done. 150 patients had clinically usable TTE images for accurate calculations. STI was calculated independently by operators experienced in TTE and BCG. Results were compared using Pearson’s R. A proprietary AI algorithm for automatically calculating the MPI, was trained over a subset of patients. Its accuracy in detecting STI was compared to that of TTE and manually calculated STI from BCG.</p> <p><strong>Results:</strong> There was a strong positive correlation (r=0.766, P&lt;0.00, 99%CI [0.691,0.824]) between the TTE and BCG derived MPI values. The result was validated over predetermined subgroups of subjects with reduced EF (EF&lt;50) and subjects with normal EF (EF&gt;=50). The AI algorithm had correlation of 0.54(p&lt;0.01) with the MPI calculated by TTE and 0.34(P&lt;0.10) with the manually calculated MPI on the BCG.</p> <p><strong>Conclusion:</strong> BCG derived manual and automated MPI correlates well with TTE derived MPI in a variety of EF fraction subgroups. Automated calculation algorithms for MPI derived from BCG remain a work under progress.</p> K. R. Nishanth, Aashit Singh, Gaurav Parchani, Gulshan Kumar, Vibhor Saran, Cholenahally Manjunath, Deepak Padmanabhan ##submission.copyrightStatement## Sat, 17 Jul 2021 12:23:25 +0000 The Correlations between Admission Heart Rate and Corrected QT Interval Prolongations with Coronary Artery Disease in Patients with Acute Coronary Syndrome <p><strong>Background: </strong>Coronary heart disease is a major cause of mortality and this health problem is reaching pandemic in both developed, and developing countries. ACS carries significant morbidity and mortality and the prompt diagnosis, and appropriate treatment is essential. HR was identified as a risk predictor of ACS. Both continuous increase in high baseline heart rate and decrease in low baseline heart rate are associated with higher risk of CVD. Decreased heart rate could also cause dispersion of atrial repolarization which, in turn, initiate cardiovascular events.</p> <p><strong>Aim: </strong>The aim of this study was to assess the correlation between heart rate and severity of coronary artery disease in patient with acute coronary syndrome.</p> <p><strong>Patients and Methods: </strong>The retrospective study was conducted on 120 patients that fulfilled the inclusion criteria were recruited from Cardiology department in Tanta university hospitals presented with acute coronary syndrome.</p> <p><strong>Results: </strong>There was highly significant difference between both groups regarding <em>admission heart rate &amp; QTc interval</em>. Both groups of low AHR&lt; 60 bpm &amp; high AHR &gt;90bpm were significantly associated with severe CAD &amp;.Mainly those patients with higher admission heart rate were more likely to have higher Syntax scores (severe coronary lesion). Also, patients with prolonged QTc had severe coronary artery diseases, higher SS &amp; high probability to suffer adverse cardiac events more than patients without prolonged QTc interval.</p> <p><strong>Conclusion: </strong>The current study showed that QTc interval prolongation and admission HR are independent predictors of the severity of coronary artery disease in patients with acute coronary syndrome.</p> Shaimaa Mohamed Amer Abo Elnoaas, Raghda Ghonimy El Sheikh, Mohamed Ahmed Abd Elaal, Ayman Ahmed El Sheikh ##submission.copyrightStatement## Tue, 20 Jul 2021 00:00:00 +0000 Correlation of Triglyceride with Coronary Artery Disease Severity in Pre-Diabetic Chronic Stable Angina Patients <p><strong>Background:</strong> Individuals with prediabetes have multiple disturbances in lipoprotein metabolism resulting from multiple combinations of insulin deficiency, insulin resistance and hyperglycemia. Dyslipidemia is the commonest complication of prediabetes and diabetes, and it predispose to premature atherosclerosis causing cardiovascular complication. The aim of this study was to assess correlation of triglyceride (TG) with coronary artery disease (CAD) severity in pre-diabetic chronic stable angina patients.</p> <p><strong>Methods: </strong>Our cross-sectional observational study was conducted on 100 pre-diabetic patients (HbA1c 5.7% to 6.4%) with different levels of TG and stable CAD, referred to Tanta university hospitals. Each patient had been subjected to adequate history taking, complete clinical examination and laboratory investigations and electrocardiogram with transthoracic echocardiography. SYNTAX score was calculated.</p> <p><strong>Results: </strong>There were significant positive correlations between TG and LDL, ratio and TLC respectively while there was a significant negative correlation between TG and HDL. There was significant positive correlation between SYNTAX and LDL, ratio and urea respectively &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;while there was high significant negative correlation between TG and HDL. TG level was significantly higher in male than female (p= 0.028). There was no significant difference in SYNTAX regarding gender. For the multivariate analysis, only LDL was a significant independent predictor for CAD.</p> <p><strong>Conclusions: </strong>There was a positive correlation between the TG and the severity of coronary lesions in pre-diabetic stable angina pectoris patients.</p> Mahmoud Mohammed Tolba, Mohamed Khalfallah, Sameh Samir Khalel, Hanan Kamel Kassem ##submission.copyrightStatement## Tue, 02 Nov 2021 00:00:00 +0000 Physical Training as a Blood Pressure Reducer and a Remodeler of Cardiac Fibers in Spontaneously Hypertensive Rats (SHR) <p><strong>Background: </strong>Hypertension is the most prevalent of all cardiovascular diseases, reaching target organs such as the heart. Blood pressure control is critical for preventing organ damage induced by hypertension.</p> <p><strong>Objective:</strong> To analyze blood pressure, heart rate, left ventricular thickness, the percentage of cardiac fibrosis and the percentage of type III collagen in Spontaneously Hypertensive Rats (SHR) submitted to swimming physical training.</p> <p><strong>Methods: </strong>The experimental groups were composed of male Wistar Kyoto (WKY) rats (309-311g), which were divided into: 1) Normotensive Sedentary group (SN) (n = 6); 2) Trained Normotensive group (TN) (n = 6); 3) Sedentary Hypertensive group (SH) (n = 6); 4) Trained Hypertensive group (TH) (n = 6). After the end of the protocol, the animals were initially anesthetized to measure blood pressure.</p> <p><strong>Results: </strong>Physical training was responsible for decreasing blood pressure (F = 16,968; p &lt;0.001) and heart rate (F = 10.710; p = 0.004) in the trained groups (normotensive and hypertensive). Moreover, training was responsible for providing an increase in the thickness of the left ventricle (F = 7,254; p = 0.014) and a reduction in the percentage of cardiac fibrosis (F = 16,081; p &lt;0.001). Furthermore, it was observed that the trained group had lower values of type III collagen (F = 13,166; p = 0.002).</p> <p><strong>Conclusions: </strong>Physical swimming training triggered a decrease in blood pressure, heart rate, the percentage of fibrosis and the percentage of type III collagen. In addition, there was also a cardiac remodeling due to the increase in left ventricular hypertrophy.</p> Mariana Molinar Mauad Cintra, Matheus Ribeiro Bizuti, Octávio Barbosa Neto, Marlene Antônia dos Reis, Lenaldo Branco Rocha, Débora Tavares de Resende e Silva ##submission.copyrightStatement## Sat, 16 Oct 2021 00:00:00 +0000 Hyperuricemia and Smoking Correlation in Egyptian Young Adults with Coronary Artery Disease: Observational Study <p><strong>Background: </strong>Young adults, especially those under 35, are often overlooked; however, previous studies have shown that coronary artery disease (CAD) incidence increases rapidly. Previous studies proved many risk factors for CAD, such as hyperlipidemia, hypertension, diabetes, and smoking. The present study ultimately aimed to figure out the correlation between Hyperuricemia (HUA) and smoking in CAD Patients under the age of 35.</p> <p><strong>Methods: </strong>This observational study included 100 young adults (18–35 years of age) suspected of CAD. We used the Gensini Score system to ascertain coronary angiography outcome and CAD; based on the number of affected vessels, localization of the segment, and the stenosis grade.</p> <p>The Gensini score being &gt; 0 indicated the presence of CAD.</p> <p><strong>Results: </strong>In young adults under 35, there was a significant correlation between HUA and CAD. The interaction between HUA and smoking had a contrast for CAD that statistically shown the existence of CAD increased in patients who have hyperuricemia and non-smokers compared to smokers.</p> <p><strong>Conclusions: </strong>By monitoring various parameters in young adults ≤ 35 years old. This study strengthens the correlation between:1) hyperuricemia and the occurrence of CAD, 2) Smoking and the CAD. Furthermore, there is a clear association between HUA and the occurrence of CAD in non-smokers.</p> Ali Youssef El-Sayed Youssef, Seham Fahmy Badr, Mohamed Ahmed Abd El-Aal, Ayman Ahmed El-Sheikh ##submission.copyrightStatement## Wed, 08 Dec 2021 00:00:00 +0000